Whole Slide Imaging
Pathology benefits from advanced innovative technologies to implement digital solutions. Whole slide imaging is a disruptive technology that can scan slides to generate digital images. The digital image can be viewed as a digital file like a slide in a microscope. Therefore, pathologists, pathology departments and scientists increasingly use full slide imaging in clinical, educational and research programs.
Figure 1．This figure shows two examples to illustrate the impact of suboptimal frozen section slides on image quality generated by WSI devices. (a) A diffuse astrocytoma with a tissue fold in the center of the field is shown that has caused the edge of the section (right edge) to be out of focus, (b) A high-grade astrocytoma with a large air bubble under the coverslip (Pantanowitz, et al. 2011).
Whole Slide Imaging Workflow
Whole slide imaging, also known as virtual microscope, refers to scanning a complete microscope slide and creating a single high-resolution digital file. These files can be effectively stored, accessed, analyzed and shared with scientists on the network using slide management technology. The following is the general workflow of whole slide imaging:
- Quickly acquire images
- Efficient data storage
- Easy and instant data sharing
- Experienced scientists provide experimental consultation
- Reasonable price and short turnaround time
CD BioSciences has advanced imaging equipment and professional technicians. We can provide you with whole slide imaging services to digitize slides in brightfield or fluorescence format. In addition, we also provide a set of quantitative digital pathology services, including computer image processing of glass slides for cell counting, co-localization of biomarkers, etc. If you have any needs, please feel free to contact us.
- Pantanowitz, Liron, et al. "Review of the current state of whole slide imaging in pathology." Journal of pathology informatics 2 (2011).
- Hanna, Matthew G., Anil Parwani, and Sahussapont Joseph Sirintrapun. "Whole slide imaging: technology and applications." Advances in Anatomic Pathology 27.4 (2020): 251-259.
*If your organization requires the signing of a confidentiality agreement, please contact us by email.
Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!