Cell Morphology Imaging Services

Cell Morphology Imaging Services

Cell morphology analysis is the quantitative characterization of cell morphology, including structural and internal component analysis, to better classify cells and identify their abnormalities, and then understand the pathogenesis of diseases. The results of cell morphology image analysis are objective and reliable, which is helpful for pathologists to make the final diagnosis, and quickly observe and treat diseases.

Three basic forms and arrangements of bacteria.Figure 1. Three basic forms and arrangements of bacteria.

Cell Morphology Imaging Analysis

CD BioSciences is a biotechnology company dedicated to providing imaging analysis services. We have professionals in the field of cell imaging analysis, advanced microscope hardware and computer image analysis software. We can provide you with high quality cell morphology imaging analysis services, and provide you with accurate and reliable original data and easy to read analysis reports.

Cell Morphology Imaging Analysis Workflow

Image-based cell morphology analysis is a high-throughput strategy for quantifying phenotypic differences between various cell populations. The general workflow of this technology includes the use of a high-throughput microscope system for image acquisition and subsequent image processing and analysis. The detailed analysis steps are as follows:

The first stage of work includes sample preparation and image acquisition.

Step 1

Experiment plan

Design your experiment, considering the instruments and reagents required for cell morphology imaging and analysis.

Step 2

Cell culture

Let cells grow under the most suitable conditions.

Step 3

Cell marker

Use selective specific fluorescent dyes to label target cell structure and target protein.

Step 4

Acquire cell images

Capture target cell images with maximum clarity and resolution.

Step 5

Cell morphology analysis

Use the cell imaging analysis software to analyze the cell morphology.

The starting point of the second stage of the workflow is a large number of images, morphological analysis of the collected cell images to obtain the required biological information.

Cell Morphology Analysis

Eight main steps transform images into quantitative information to support experimental conclusions.

Image analysis
Image quality control
Preprocessing extracted features
Dimensionality reduction
Downstream analysis
Assay quality assessment
Measuring profile similarity
Single-cell data aggregation

Delivery

Morphological feature distribution histogram
Data on the morphological state of a single cell or cell group
Heat map of distance matrix
Other data that you need

Our Advantages

  • Computer-aided, automated processing
  • Accurate and reliable results
  • Used to assess the health and quality of cell culture
  • Experienced scientists provide experimental consultation
  • Reduced workload and cost

At CD BioSciences, the entire process of cell morphology imaging analysis is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs for cell morphology imaging analysis, please feel free to contact us. We will customize the personalized experimental scheme for you according to your needs.

Reference
  1. Caicedo, Juan C., et al. "Data-analysis strategies for image-based cell profiling." Nature methods 14.9 (2017): 849-863.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!

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