RNA Translation Imaging Services

RNA Translation Imaging Services

mRNA translation is a key step in gene expression, which allows the genetic information carried by the mRNA to flow into the protein. mRNA translation is regulated by a variety of factors and gene specificity. The accurate operation of this process can ensure the expression of proteins in cells, which is essential for maintaining cell functions. Therefore, the development of imaging methods that can visually analyze the translation of a single mRNA in living cells has become a research hotspot.

DNA and RNA transcription and translation.Figure 1. DNA and RNA transcription and translation.

RNA Translation Imaging Analysis

CD BioSciences has been committed to the research and development of fluorescent probes and living cell imaging technology for many years. In order to study translation heterogeneity and translation kinetics, we used high-affinity probes and single-molecule microscopes to image the translation kinetics of a single RNA in living cells and quantify the process of synthesizing nascent polypeptide chains from a single mRNA.

RNA Translation Imaging Analysis Workflow

The following are the specific steps of RNA translation imaging analysis:

Step 1

Fill in the online form to submit your requirements for RNA translation imaging analysis.

Step 2

Send us the DNA / RNA / mRNA that need to be imaged and analyzed.

Step 3

We use high-affinity probes and single-molecule microscopes to image the translation kinetics of a single RNA in living cells

Step 4

After the experiment is completed, we will send the sample and experimental data to you.


Single mRNA ribosome density
Translation initiation and elongation
Quantification of translation site mobility and high-level structure
Quantitative analysis of mRNA attenuation
Provide other data according to your needs

Our Advantages

  • High spatial resolution, high signal-to-noise ratio
  • Visually analyze molecular interactions
  • Experienced scientists provide experimental consultation
  • Reasonable price and short turnaround time

CD BioSciences has a professional team and advanced imaging equipment. The entire process of RNA translation imaging analysis is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us. We will provide you with a one-stop service, including cell culture, image acquisition and image analysis.

  1. Khuperkar D, Hoek T A, Sonneveld S, et al. Quantification of mRNA translation in live cells using single-molecule imaging[J]. Nature protocols, 2020, 15(4): 1371-1398.
  2. Morisaki T, Stasevich T J. Quantifying single mRNA translation kinetics in living cells[J]. Cold Spring Harbor perspectives in biology, 2018, 10(11): a032078.

*If your organization requires the signing of a confidentiality agreement, please contact us by email.

Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!

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