Drug Targets Imaging Analysis
Protein structure is the basis for rational drug molecular design. The targets of many drug molecules are proteins or enzymes, and their active sites or binding sites are the sites of drug action. These parts have specific spatial shapes and can only bind to specific molecules. When designing a new drug molecule, it is necessary to make the structure of the drug small molecule complementary to the active site of the target, so that the drug molecule can be combined with the target to exert the drug effect. The drug design based on the molecular structure of the target requires in-depth research on the molecular structure of the target protein, obtaining relevant information, and establishing the protein structure model of the target with the help of computer technology. Therefore, imaging analysis of drug target structures is crucial for the development of new drugs.
Figure 1. G protein-coupled receptor is an important drug target.
Drug Targets Imaging Analysis
X-ray diffraction is regarded as the gold standard method for protein structure determination and can be used to determine high molecular weight structures of several hundred kDa. However, the three-dimensional structures of various drug targets such as GABAA receptors, NMDA receptors, and EGFR receptors are difficult to analyze by X-ray diffraction crystallography. In recent years, with the development of imaging technology, high-resolution electron microscopy, confocal laser scanning microscopy and fluorescence correlation spectroscopy have been used to study the structure of various drug targets, which provides an important theoretical basis for drug research and development.
CD BioSciences has been committed to the development of imaging technology for many years. We have a professional team composed of researchers with many years of working experience in the field of imaging analysis. CD BioSciences can provide you with imaging analysis services for a series of drug targets, and then provide you with information about the target structure and the interaction between the target and other proteins. So that you can fully study the targets of interest. All this information can ensure that your subsequent drug research and development is carried out on a reasonable basis.
Nuclear Receptors Imaging Analysis
Epidermal Growth Factor Receptor Imaging Analysis
NMDA Receptors Imaging Analysis
Chemokine Receptors Imaging Analysis
Prostanoid Receptors Imaging Analysis
GABAA Receptors Imaging Analysis
If you have any needs, please feel free to contact us. We will design a personalized imaging analysis plan for you according to your needs and provide you with accurate and repeatable experimental data.
*If your organization requires the signing of a confidentiality agreement, please contact us by email.
Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!