Cell adhesion is the basic condition for maintaining the stability of tissue structure, and it is also the regulating factor of cell movement and function. It can be divided into two categories: cell-cell adhesion and cell-matrix adhesion. Many cells in the body, such as epithelial cells, need to be firmly fixed in a certain place to function; Other cells, such as leukocytes, are active in movement and need to constantly regulate cell adhesion. The change of cell adhesion also plays an important role in the process of tumor metastasis. The establishment of an experimental method for measuring cell adhesion in vitro provides a very effective method for the discovery of adhesion molecules and the study of the effects of intercellular adhesion.

Figure 1. Schematic of cell adhesion (Wikipedia).

Cell Adhesion Imaging Analysis

Cell adhesion is a key biological and biomedical parameter that defines cell differentiation, cell migration, cell survival, and disease states. Currently, a variety of tools have been developed to monitor various biochemical and mechanical cell adhesions. Traditional experiments provide information on cell interactions and their final results, but other important information is difficult to evaluate. In order to obtain more precise information, CD BioSciences can monitor cell adhesion and cell-substrate separation through time-lapse imaging.

Cell Adhesion Imaging Analysis Workflow

Delivery

Our Advantages

• High-sensitivity optical system to capture high-quality pictures
• No need to worry about quenching or damage leading to reduced activity
• Experienced scientists provide experimental consultation
• Reasonable price and short turnaround time

CD BioSciences has a professional team and advanced imaging equipment. The entire process of cell adhesion imaging analysis is operated by experienced technicians to ensure the accuracy of the experiment. If you have any needs, please feel free to contact us. We will provide you with personalized cell adhesion imaging analysis services according to your needs.

1. Ehrlich, Jason S., Marc DH Hansen, and W. James Nelson. "Spatio-temporal regulation of Rac1 localization and lamellipodia dynamics during epithelial cell-cell adhesion." Developmental cell 3.2 (2002): 259-270.
2. Khalili, Amelia Ahmad, and Mohd Ridzuan Ahmad. "A review of cell adhesion studies for biomedical and biological applications." International journal of molecular sciences 16.8 (2015): 18149-18184.

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Please note: Our services can only be used for research purposes. Do not use in diagnostic or therapeutic procedures!