Arthritis Fluorescent Imaging Panel
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Catalog NO: VIR030307
Size: 6 Vials
Introduction:Detect molecular players in arthritis pathology in vivo with Arthritis Fluorescent Imaging Panel. Standard methods to assess arthritis in animal models typically involve external measurements of limbs such as paw volume, paw thickness, and redness. While these methods determine the overall progression of disease, they do not access the underlying biology associated with the visible effects of the disease. Since arthritis involves not only inflammation pathways but also changes in vasculature and bone morphology, using fluorescent agents that measure each of these changes individually allow for a more complete assessment of the overall clinical pathology. Arthritis fluorescent panel contains a carefully selected, pre-validated bundle of probes designed for researchers to gain a better understanding of arthritis disease and its progression.
Formulation:Pan Cathepsin 680: Pan-cathepsin activatable probe (Lysosomal marker of inflammatory cells)
Vascular 750: Vascular probe (Leaks into sites of edema)
Osteo 680: Bone turnover targeted probe (Detects areas of exposed hydroxyapatite)
MMP 680: Pan-MMP activatable probe (Secreted marker of inflammatory cells, bone/cartilage degradation)
Cat K 680 FAST: Cathepsin K activatable probe (Secreted marker of osteoclasts, bone degradation)
Cat B 750 FAST: Cathepsin B activatable probe (Lysosomal marker of inflammatory cells)
Vascular 750: Vascular probe (Leaks into sites of edema)
Osteo 680: Bone turnover targeted probe (Detects areas of exposed hydroxyapatite)
MMP 680: Pan-MMP activatable probe (Secreted marker of inflammatory cells, bone/cartilage degradation)
Cat K 680 FAST: Cathepsin K activatable probe (Secreted marker of osteoclasts, bone degradation)
Cat B 750 FAST: Cathepsin B activatable probe (Lysosomal marker of inflammatory cells)
Category:Fluorescent Imaging Panels
Shipping Condition:Blue Ice
Therapeutic Area:Arthritis
Intended Use:For research use only. Not for use in diagnostic procedures.
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